Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw
Graphene-infused pillow ODM factory Taiwan
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan pillow ODM development service
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China insole ODM design and production
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam high-end foam product OEM/ODM
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan foot care insole ODM development factory
Photograph of a skeleton of the early non-mammalian synapsid (ancient mammal relative) Edaphosaurus on display at the Field Museum of Natural History. Credit: Photograph by Ken Angielczyk Researchers overturn the long-standing hypothesis that mammal ancestors moved like modern lizards and discover there is much more to the evolution of the mammal backbone. The backbone is the Swiss Army Knife of mammal locomotion. It can function in all sorts of ways that allows living mammals to have remarkable diversity in their movements. They can run, swim, climb and fly all due, in part, to the extensive reorganization of their vertebral column, which occurred over roughly 320 million years of evolution. Open any anatomy textbook and you’ll find the long-standing hypothesis that the evolution of the mammal backbone, which is uniquely capable of sagittal (up and down) movements, evolved from a backbone that functioned similar to that of living reptiles, which move laterally (side-to-side). This so called “lateral-to-sagittal” transition was based entirely on superficial similarities between non-mammalian synapsids, the extinct forerunners of mammals, and modern-day lizards. A New Approach to Evolutionary Analysis In a paper published on March 2, 2021, in Current Biology, a team of researchers led by Harvard University challenge the “lateral-to-sagittal” hypothesis by measuring vertebral shape across a broad sample of living and extinct amniotes (reptiles, mammals, and their extinct relatives). Using cutting-edge techniques they map the impact of evolutionary changes in shape on the function of the vertebral column and show that non-mammalian synapsids moved their backbone in a manner that was distinctly their own and quite different from any living animal. The team, led by first author Katrina E. Jones, former Postdoctoral Researcher, Department of Organismic and Evolutionary Biology, Harvard University, found that while the degree of sagittal bending does increase during mammal evolution, the backbones of the earliest synapsids were optimized for stiffness and the evolutionary transition to mammals did not include a stage characterized by reptile-like lateral bending. Instead, they discovered that modern lizards and other reptiles have a unique backbone morphology and function that does not represent ancestral locomotion, and that the earliest ancestors of mammals did not move like a lizard, as scientists previously posited. Modern Reptiles Are Not Living Fossils “The long-held idea that there was a transition in mammal evolution directly from lateral to sagittal bending is far too simple, said Senior author Stephanie Pierce, Thomas D. Cabot Associate Professor in the Department of Organismic and Evolutionary Biology and curator of vertebrate paleontology in the Museum of Comparative Zoology at Harvard University. “Lizards and mammals diverged from one another millions of years ago and they’ve each gone on their own evolutionary journey. We show that living lizards don’t represent any sort of ancestral morphology or function that the two groups would have had in common so long ago.” Co-author Ken Angielczyk, MacArthur Curator of Paleomammalogy, Negaunee Integrative Research Center, Field Museum of Natural History, agreed, “Reptiles have been evolving just as long as mammals and because of that there’s just as much time for changes and specializations to accumulate for reptiles. If you look at the vertebrae of a modern lizard or crocodile their vertebrae are actually very different from early ancestors of mammals and reptiles that lived at the same time around 300 million years ago. Both living mammals and reptiles have accumulated their own set of specializations over evolutionary time.” 1. Lateral-to-Sagittal: Illustration comparing the back movements of a lizard, which uses primarily lateral (side-to-side) movements, and a mammal, which uses sagittal (up-and-down) movements when running. Credit: Illustrations by Stephanie Smith. 2. Thrinaxodon Puzzle: Life reconstruction of Thrinaxodon, an extinct mammal forerunner, show how the backbone was pieced together over evolutionary time. Credit: Illustration Copyright April Neander. Jones and co-authors, including former Harvard graduate student Blake Dickson, PhD ’20, began by measuring the shape of the vertebrae of a range of reptiles, mammals, salamanders, and some fossil non-mammalian synapsids. The specimens came from museum collections all over the world, with modern animal skeletons primarily from the Museum of Comparative Zoology (MCZ), and fossil synapsids from the MCZ, the Field Museum of Natural History, and various other museums in the USA, Europe, and South Africa. “We first had to quantify the shape of the vertebrae and that’s actually a little bit tricky,” said Jones. “Each vertebral column is made up of multiple vertebrae and when you have different numbers of vertebrae their shapes and functions might divide up in different ways.” They selected five vertebrae at equivalent locations from each of the vertebral columns and measured their shapes across the different animals in three-dimension. The results showed quantitatively that non-mammalian synapsid vertebrae are very different from the vertebrae of modern mammals, and critically also from the vertebrae of lizards and other reptiles. Next, the researchers examined how the vertebrae may have functioned using data from their previous work that compared vertebral shape to the degree of vertebral motion in living lizards and mammals, providing a crucial link between form and function. The data enabled the researchers to map variation in vertebral function across a broad sample of animals, including the fossils, which allowed them to reconstruct the precise combination of functional traits that described each group of animals. Functional Tradeoffs Reveal Distinct Evolutionary Strategies “Our team’s approach to data analysis is exciting as it can reveal how different backbone shapes may result in different functional tradeoffs,” Pierce said. Reptiles, for example, are very good at lateral bending, but are unable to move their spine up and down like mammals. “In addition to lateral and sagittal bending we also examined other functions of the backbone and then determined the optimal combination of tradeoffs for mammals, reptiles, and non-mammalian synapsids,” said Pierce. “We were able to show that non-mammalian synapsids have a different combination of functions in their backbone to both living reptiles and mammals,” Jones said, “and in the course of that evolution they weren’t just traversing from the reptile-like lateral to the mammal-like sagittal bending, they were actually on a completely distinctive path in which they were evolving from a separate condition.” “The historical expectation is that the synapsid ancestors of mammals were making the same set of tradeoffs that modern reptiles do. But it turns out that they have an entirely different set of tradeoffs,” Angielczyk said. “The expectation that reptiles would retain ancestral locomotor patterns that existed over 320 million years ago is too simple.” From Stiff Backbones to Mammalian Versatility The results show the backbones of non-mammalian synapsids were actually quite stiff and completely unlike those of lizards which are very compliant in the lateral direction. Further, during the evolution of mammals, new functions were added to this stiff ancestral foundation, including sagittal bending in the posterior back and twisting up front. The addition of these new functions was pivotal in building the functionally diverse mammalian backbone, allowing modern-day mammals to run really fast and rotate their spine to groom their fur. “By rigorously analyzing the fossil record, we are able to reject the simplistic lateral-to-sagittal hypothesis for a much more complex and interesting evolution story,” Pierce said. “We are now revealing the evolutionary path towards the formation of the unique mammalian backbone.” The study is part of a series of ongoing projects on the evolution of the mammal backbone, piecing together its development, morphology, function, and evolution. “We still don’t have the whole story,” said Jones, “but we are getting close.” The researchers are now using three-dimensional modeling of the vertebrae to understand how the ancestors of mammals moved. “We are now testing our previous studies with CAD-assisted three-dimensional models,” said Jones. “So far it’s working quite well and appears to support what we found in this paper.” Reference: “Adaptive landscapes challenge the “lateral-to-sagittal” paradigm for mammalian vertebral evolution” by Katrina E. Jones, Blake V. Dickson, Kenneth D. Angielczyk and Stephanie E. Pi, 2 March 2021, Current Biology. DOI: 10.1016/j.cub.2021.02.009 Katrina E. Jones is currently Presidential Fellow at the University of Manchester, UK. Blake Dickson is currently a postdoctoral researcher in the Department of Evolutionary Anthropology at Duke University.
Scientists were able to examine tens of millions of three-dimensional locus groupings with the help of the new technology which they named Pore-C. The human genome’s inner workings could be revealed through new Cornell-developed technology. Researchers from Oxford Nanopore Technologies, Weill Cornell Medicine, and the New York Genome Center have created a new technique to evaluate the three-dimensional structure of the human DNA, or how the genome folds, on a massive scale. The genome is the entire set of genetic instructions, either DNA or RNA, that allow an organism to function. Using this technique, the researchers showed that groups of simultaneously interacting regulatory elements in the genome, as opposed to pairs of these elements, may influence cell activity, including gene expression. Their research, which was recently published in the journal Nature Biotechnology, may help clarify the connection between cellular identity and genome structure. “Knowing the three-dimensional genome structure will help researchers better understand how the genome functions, and particularly how it encodes different cell identities,” said senior author Dr. Marcin Imieliński, associate professor of pathology and laboratory medicine and computational genomics in computational biomedicine at Weill Cornell Medicine and a core member of the New York Genome Center. “The ways that we’ve had to study genome structure have given us amazing insights, but there have also been key limitations,” he said. For example, previous technology to examine the genome’s three-dimensional structure enabled researchers to investigate how often two loci, or physical sites on the genome, interact with one another. Traditionally, pairs of loci known as enhancers and promoters—components in the genome that interact with one another to control gene expression—have been discovered. Information about these pairings offers incomplete insight into genome structure and function. For instance, linking a folding pattern to how the genome encodes for a specific cell identity—like a liver, lung, or epithelial cell—has been difficult, said Dr. Imieliński, who is also a member of the Englander Institute for Precision Medicine and the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine. Scientists have theorized that this folding influences gene expression. “But how cell types are encoded, particularly in the structure of DNA, has been a mystery,” he said. Developing the Pore-C Assay Dr. Imieliski and his research team, which included first author Aditya Deshpande, a recent graduate of the Tri-Institutional Ph.D. Program in Computational Biology & Medicine who worked in Dr. Imieliski’s lab, created a new genome-wide assay and algorithm that allows them to study groups of loci rather than just pairs. They adapted Hi-C (chromatin conformation capture), a standard approach that evaluates a combination of DNA and protein to assess three-dimensional genome structure, to nanopore sequencing, or the high-throughput sequencing of long, continuous strands of DNA molecules. The new test, named Pore-C, allowed the researchers to examine tens of millions of three-dimensional locus clusters. Identifying Key DNA Groupings for Cell Identity They also developed statistical methods to determine which locus groupings were important, based on whether they interacted cooperatively to affect gene expression. “Many three-dimensional interactions of the genome are not important,” Dr. Imieliński said. “Our analytic methods help us prioritize the group interactions that are likely to matter for genome function.” As a key finding of the study, the researchers found that the most significant cooperative groupings of DNA elements occurred around genes associated with cell identity. Future experiments will explore which specific groupings of genomic components are essential for various aspects of cell identity. The new technology may also help researchers to understand how stem cells, the immature, master cells of the body, differentiate into different cell types. In addition, researchers may be better able to understand abnormalities in cancer cells. “In the future, this technology may be really helpful in understanding how cancer cell genomes are rearranged, and how those rearrangements drive the altered cell identities that enable cancers to grow and spread,” Dr. Imieliński said. Reference: “Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing” by Aditya S. Deshpande, Netha Ulahannan, Matthew Pendleton, Xiaoguang Dai, Lynn Ly, Julie M. Behr, Stefan Schwenk, Will Liao, Michael A. Augello, Carly Tyer, Priyesh Rughani, Sarah Kudman, Huasong Tian, Hannah G. Otis, Emily Adney, David Wilkes, Juan Miguel Mosquera, Christopher E. Barbieri, Ari Melnick, David Stoddart, Daniel J. Turner, Sissel Juul, Eoghan Harrington and Marcin Imieliński, 30 May 2022, Nature Biotechnology. DOI: 10.1038/s41587-022-01289-z
Model to estimate skeletal kinematics. Credit: Julia Kuhl A new technique has been developed to track and measure the movement of skeletons in freely moving rodents. How can researchers accurately and precisely measure the motion of a skeleton in a furry animal as it moves through its environment? The Max Planck Institute for Neurobiology of Behavior – caesar has developed a new method that involves constructing a skeleton model which calculates bone joint movement using anatomical principles such as joint rotation limits and body movement speeds. This approach allows for a better understanding of how animals interact with their surroundings and can potentially reveal the connection between neuronal activity and complex behaviors such as decision-making, as the brain and spinal cord control movement. Have you ever thought about the motion of your skeleton as you go about your daily activities? X-ray images may come to mind when we think about this question. But how can we measure the motion of a skeleton in a moving animal that interacts with its environment without using x-rays? And why is this important? Studying the freely moving animal can provide unique insights into how animals behave and make decisions, such as avoiding predators, finding mates, and raising their young. While many studies have measured animal behavior, studies that measure the mechanics of how they move have been missing. But as activity in the central nervous system ultimately leads to decisions that are enacted through body movements, measuring these mechanics and relating them to neural activity is essential for gaining deep insights into brain function. Credit: MPINB Without an X-ray machine, analyzing movements of individual bones is extremely challenging as occluding overlaying fur, skin, and soft tissue make it complicated to get a measurement of the skeleton’s motion. Recently, several advanced machine-learning methods have been able to accurately measure an animal’s pose and even changes in an animal’s facial expression; however, so far none of the existing techniques have been able to track the changes in bone positions and joint motion under visible body surface. Researchers of the department Behavior and Brain Organization at the Max Planck Institute for Neurobiology of Behavior in Bonn, headed by Jason Kerr, have now developed a videography-based method for 3D-tracking the skeleton at the resolution of single joints in untethered animals while they interact with their environment. Their Anatomically Constrained Model (ACM) is based on an anatomically grounded skeleton that infers the skeletal kinematics of an animal as it moves freely around. Skeleton Motion in Freely Moving Animals From this data it was possible to measure the inner workings of a skeleton, moment to moment, as the animals jumped, walked, stretched, and ran around. This new approach can be applied to multiple furry species such as mice and rats of different sizes and ages. To ensure that the data was right, the researchers worked with colleagues from the Max Planck Institute for Biological Cybernetics in Tuebingen actually using MRI scanning of the animals to compare the ACM model to the actual skeleton. “Our new method is relatively simple, tether-free, and uses overhead cameras. It solves many problems associated with tracking freely moving rodents, especially those that are covered in fur and when the body covers the legs and feet” says Jason Kerr, who ran the study together with Jakob Macke from Tuebingen University. One of the next steps is to combine this approach with simultaneous recordings from neurons in the brain using the miniature head-mounted multiphoton microscopes the researchers at the Max Planck Institute for Neurobiology of Behavior have developed. This would allow to exactly correlate neural activity with actual behavior to find out more about how the brain controls even complex behavior. The researchers will also apply their new method to measure motion kinematics in other animal species in more natural environments and simultaneously in multiple, interacting animals. “Using our new method, we will on one hand gain further insights on how animals interact with their environment and, on the other hand, we hope to gain knowledge of how animals interact with each other,” says Jason Kerr. Reference: “Estimation of skeletal kinematics in freely moving rodents” by Arne Monsees, Kay-Michael Voit, Damian J. Wallace, Juergen Sawinski, Edyta Charyasz, Klaus Scheffler, Jakob H. Macke and Jason N. D. Kerr, 17 October 2022, Nature Methods. DOI: 10.1038/s41592-022-01634-9
DVDV1551RTWW78V
Indonesia OEM insole and pillow supplier 》reducing complexity, increasing product valueTaiwan foot care insole ODM development factory 》trusted by clients across wellness, footwear, and bedding industriesVietnam neck support pillow OEM 》performance-first thinking from development to delivery